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Aids: from a death sentence to living life
The first drug against HIV was AZT in 1989, but it was not until 1996 that 'the Lazarus effect' was seen in US hospitalsThe first children with Aids were identified in the USA in 1983, two years after...
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This week's cultural highlights: Mary Shelley and the Civil Wars
Our critics' picks of this week's openings, plus your last chance to see and what to book now• Which cultural events are in your diary this week? Tell us in the comments belowOpening this...
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Ana – review
Traverse, EdinburghBinary thinking is at the heart of this fascinating, if ultimately frustrating new play. It is the result of a two-way collaboration between Scotland's Stellar Quines and Canada's...
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Italian spa town prepares for onslaught of Russian oligarchs
Montecatini Terme plans to erect signs in Cyrillic after Svetlana Medvedeva, wife of outgoing president, visits its luxury hotelA luxury Tuscan spa hotel which has hosted the likes of Giuseppe Verdi,...
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Kofi Annan leaves Syria after talks with Assad
Former UN secretary general says he offered Syrian president concrete proposals 'which will have a real impact on the ground'The international envoy Kofi Annan has left Syria without a deal to end the...
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How Nick Clegg and Shirley Williams lost the great NHS debate
Turmoil at Liberal Democrat spring conference as party leadership fails to win backing of delegates for health billFew organisations can debate for three days whether to stage a debate, hold the...
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Public health: saving lives and spending less | Sarah Harper
The US healthcare system costs far more than in Japan, where emphasis is placed on lifestyleWhat makes the most difference to a nation's health? Is it spending money on hospitals, medical equipment,...
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Paul Lewis – review
St George's, BristolThe very intensity of Paul Lewis's commitment to the cause of Franz Schubert has conferred a special status on his series presenting the piano music of the composer's last six...
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Greek opposition leader attacks debt deal and hints at early election
Antonis Samaras, head of the New Democracy (ND) party, criticises latest bailout package in bid to work outside coalitionThe opening shots in Greece's next general election campaign were fired on...
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LMFAO – review
Shepherd's Bush Empire, LondonIt's likely that many of the fans bouncing off the walls at this show have no idea they're watching pop royalty. MC Redfoo, the bawling livewire who comprises half of...
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Open door: The readers' editor on… the inclusion of controversial titles in...
Like every good bookseller, the Guardian employs a selection process, but it is obliged to tell potential customers when this is not the caseIf you put the words Mein Kampf into the search function of...
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Coalition breakdown may come sooner than we think | Jackie Ashley
The NHS row, mansion tax v tycoon tax, Lords reform: the Tories and the Lib Dems look to be heading for an all-out warA conference is a wonderful thing: without today's vote against the NHS changes at...
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As Apple and Twitter have found, digital revolution can take time
It is easy to be seduced by the power of an idea – and hard to know how to cope with the long wait for dollarsApple's iPad … well, it should have had a name, came out this week, but perhaps the number...
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A shepherd's grave
Borrowdale, Lake District: There was no sign on the summit of the septuagenarian shepherd's grave I had come to pay my respects to following his recent burialA bitter north wind hurtled across the dome...
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Blue Touch Paper – review
Kings Place, LondonColin Towns, the one-time rock pianist and TV and film composer, paints big musical canvases, full of colliding characters who sound like relatives of Stravinsky, Zappa, the Beatles,...
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Nicolas Sarkozy courts rightwing voters with Schengen zone threat
French president who is trailing behind rival François Hollande makes hardline speech on immigration in mega-rallyNicolas Sarkozy has stepped up his courtship of hard-right voters by threatening to...
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Doonesbury strip on Texas abortion law dropped by some US newspapers
Several papers decline to use cartoon strip, which depicts state-required sonograms as Republican-approved rapeA Garry Trudeau Doonesbury strip lampooning Texas legislation on abortion has been pulled...
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Saudi Arabia's female students stage cleaning protest
Rare display of dissent in the kingdom as university students boycott classes to protest against poor servicesThousands of students at an all-female university in Saudi Arabia boycotted classes at the...
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Sir David Frost: 'Today, Lord Lucan is as good as we'll get'
The superlative interviewer on the one that got away – or has he? – and his new show on BBC4. And after almost half a century working on TV, what surprises him most?How do you interview Sir David...
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Levels of trust hit an all-time low in Afghanistan campaign
Mass killing of Afghan civilians by US soldier, like the backlash against the Qur'an-burning, displays the fragility of this conflictThe mass killing of Afghan civilians by a US soldier in Kandahar was...
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