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Game warns investors as shares collapse

Game Group shares, which have already lost more than 95% of their value over the past year, crashed a further 65% this morningGame Group, the computer game retailer that is unable to sell keenly...

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Right-to-die hearing of man with locked-in syndrome gets go-ahead

Court rules that legal action seeking right for doctor to be able to lawfully end Tony Nicklinson's 'intolerable' life should proceedA high court judge has ruled that the right-to-die case of a man who...

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Mild and dry weather expected to remain all week

Above-average temperatures set to continue across most of UK with prospect of hosepipe bans in London and south-eastOne of the warmest weekends of the year in the UK so far will be followed by...

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Gemma McCluskie's brother appears in court charged with her murder

Tony McCluskie is accused of killing the former EastEnders actor, whose torso was found floating in a canalThe brother of a former EastEnders actor has appeared in court accused of murdering her and...

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Taliban vow revenge for US soldier's attack on Afghans

Statement on website blames 'sick-minded American savages' and promises revenge for 'every single martyr'The Taliban have vowed revenge for an "inhumane attack" in which a US soldier allegedly murdered...

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Kauto Star gets go-ahead to run in the Cheltenham Gold Cup

• Paul Nicholls reports chaser on course for Festival highlight• Second-favourite worked well in Monday schooling sessionKauto Star, the most popular steeplechaser since Desert Orchid, will make what...

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Julius Malema begs for ANC return after expulsion

South African youth leader apologises to party's leadership after being thrown out this month for sowing divisionsA renegade youth leader expelled by South Africa's governing party has made a surprise...

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Art historians say they have found evidence of 'hidden' Leonardo da Vinci

Researchers who drilled through a fresco in Florence's town hall say paint used by Leonardo was found in the cavity behindResearchers in Florence say they are one step closer to proving a lost...

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Right-to-die statement: Tony Nicklinson says stroke left 'no dignity or privacy'

Married father of two, who is paralysed below the neck, describes 'intolerable' life in statement included in judge's rulingTony Nicklinson was a "very active and outgoing man" before having a stroke...

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Eating red meat raises 'substantially' risk of cancer or heart disease death

Data collected over 28 years reveal striking link – and show that consuming fish or poultry instead contributes to a longer lifeRegularly eating red meat increases significantly risk of death from...

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Budget negotiations go to wire as Clegg and Cameron fail to agree

Senior ministers will hold final budget meeting 48 hours before chancellor unveils plans in CommonsDavid Cameron and Nick Clegg are to take their negotiations on next week's budget down to the wire...

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Iain Duncan Smith: early intervention crucial to prevent social breakdown

Local authorities must switch spending focus from consequences to causes, work and pensions secretary urgesThe British government is spending £25bn a year on the consequences of social breakdown and a...

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Afghanistan and the soldiers without a safety catch | Giles Fraser

We should think harder before we deploy troops. They are dehumanised by training, and made to killIn 1947 the official US historian of the second world war, Brigadier General SLA Marshall, published...

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Warren Gatland tops list of candidates for role of Lions head coach

• Gatland was forwards coach on 2009 to South Africa• Man-management skills have been praised by playersWarren Gatland is understood to be the preferred candidate of the British and Irish Lions...

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Letters: Support for libraries

Today hundreds of library users travel to Westminster to highlight the vital role of our libraries and library staff. They are speaking up for millions of people – young and old – who use public...

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European ministers locked in talks over Greece's worsening finances

Optimism that second tranche of funds – €130bn – will finally be released after success of private sector bond swapEurozone leaders are locked in talks over how to tackle Greece's deteriorating...

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Cheltenham Festival odds-on shots could deliver bookies knockout blow

Five hot favourites could give punters a memorable meetingAccording to betting folklore, the late Kerry Packer once took part in a poker tournament in Las Vegas where one of his opponents, a brash...

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The Cure to play Reading festival for first time in three decades

Foo Fighters and Kasabian also announced as headliners for Reading and Leeds events on August bank holidayFoo Fighters, the Cure and Kasabian are to headline this year's Reading and Leeds Festivals.The...

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Hurricane Fly on course for Champion Hurdle win at Cheltenham Festival

• Willie Mullins-trained runner can follow up 2011 victory• Menorah could challenge hot favourite Sprinter SacreHistory has a habit of repeating itself in the Champion Hurdle and Hurricane Fly can...

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F1 ready to roar with no Italian in the cockpit | Richard Williams

The new season seems destined to be historic for an absence though a dozen nations have drivers on the gridIf the French more or less invented grand prix racing at the beginning of the last century and...

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